Synthetic Dental Membrane

Epi-Guide® is fabricated from polylactic acid and is the only bio-resorbable synthetic dental membrane with a unique 3-layer technology to provide predictable healing while maintaining sufficient rigidity.

Epi-Guide is indicated for use as an adjunct to periodontal restorative surgeries in the treatment of periodontal defects following established surgical procedures.

High-tech Architecture — Maintains Space / Helps Arrest Epithelial Migration
Synthetic Construction — Avoid Risks of Disease from Biological Products
Completely Resorbable — Second Surgery Unnecessary to Remove Membranes


Visible Healing in Your Patients

  1. Forms a natural barrier to promote soft-tissue healing.
  2. Maintains architecture and structural integrity for up to 20 weeks after implantation.
  3. Complete bioresorption occurs between 6 and 12 months.
  4. Regenerates tissue despite flap recession or if primary closure is not obtained.

The Epi-Guide Bioresorbable Barrier Matrix is a synthetic dental membrane designed for use as an adjunct to periodontal restorative surgeries and assists in the regeneration of bone and periodontal support tissues. It is a porous, three-dimensional matrix fabricated from D, D-L, L polylactic acid, a bioresorbable polymer with a long history of safe medical use. The barrier’s three-layer construction is deigned to attract, trap, and retain fibroblasts and epithelial cells while maintaining space around teeth for development of bone and periodontal support tissues. The Epi-Guide maintains its architecture and structural integrity for 20 weeks after implantation with complete bioresorption between 6-12 months.

The Epi-Guide Barrier is a hydrophilic synthetic dental membrane that quickly absorbs blood fluid and clinical investigations have revealed that, once implanted in the body, Epi-Guide functions to support the initial blood clot and maintain competence of collateral circulation. Should the barrier become exposed or if primary closure is not obtained, clotted blood within the barrier provides a natural matrix which allows tissue to quickly grow and cover most exposures. The Epi-Guide Barrier is self-supporting and can be used in many situations without support from bone grafting materials.

Layer 3: Gingival Interface

synthetic dental membrane - epiguide membraneNumerous voids and intercommunicating pathways enhance fibroblast infiltration and cell attachment. 

Layer 2: Inner Surface
Inner labyrinth creates pathways, while internal chambers enable collateral circulation and flow of interstitial fluid in the membrane.

Layer 1: Defect Interface
Limited porosity supports an uptake of fluid, helps adherence to the tooth surface, and inhibits fibroblast movement.

more info (PDF)

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